The Diabetes Control and Complication Trial reported that tight blood glucose control noticeably slows the complications of diabetes therefore many diabetic patients struggle to manage their blood glucose levels with existing treatments. This chronic disease results from defects in insulin secretion and/or peripheral insulin resistance, that both deteriorate glycemic control. The prevalence of T2DM is increasing at an alarming rate, so that the number of Iranian adults suffering from diabetes was more than four millions in 2011 and has been raised by 35% over the past years. Type 2 diabetes mellitus (T2DM) remains a serious public health problem, with high rates of morbidity and mortality in low- or middle-income countries. However, the modest beneficial effects of chromium supplementation on insulin resistance as indicated by HOMA-IR and lipid profile were found. In this study, oral supplementation with 400 µg CrPic for eight weeks did not alter FBG concentration as well as anthropometric parameters in individuals with T2DM. Results of analysis of covariance showed that there were significance differences between groups in total cholesterol, low density lipoprotein cholesterol and HOMA-IR at the end of the intervention adjusting for baseline levels (p = 0.035, 0.030 and < 0.001, respectively). No significant changes were observed for weight, body mass index, and fasting blood glucose (FBG) in both groups while intra-groups changes in homeostatic model assessment for insulin resistance (HOMA-IR) value was significant (p < 0.05). The patients were recommended not to change their normal diet, life style and medication. Anthropometric indices and metabolic factors were measured at the beginning, and at end of the study. One group received 400 µg CrPic per day and the other group took placebo the intervention duration was 8 weeks. The patients with T2DM (n = 52) were randomly allocated into 2 groups. This study was conducted to evaluate the effects of chromium picolinate (CrPic) supplementation on the glycemic status and lipid profile in patients with T2DM. Portions of this document last updated: Feb.Type 2 diabetes mellitus (T2DM) is a serious public health problem accompanies with several complications. This product is available in the following dosage forms: Normal daily recommended intakes for chromium are generally defined as follows:īirth to 3 years of age-10 to 80 micrograms (mcg) a day.ħ to 10 years of age-50 to 200 mcg a day.Īdolescents and adults-50 to 200 mcg a day. Recommended Nutrient Intakes (RNIs) are used to determine the amounts of vitamins, minerals, and protein needed to provide adequate nutrition and lessen the risk of chronic disease.īecause a lack of chromium is rare, there is no RDA or RNI for it. DV replaces the previous designation of United States Recommended Daily Allowances (USRDAs). RDAs for a given nutrient may vary depending on a person's age, sex, and physical condition (e.g., pregnancy).ĭaily Values (DVs) are used on food and dietary supplement labels to indicate the percent of the recommended daily amount of each nutrient that a serving provides. Recommended Dietary Allowances (RDAs) are the amount of vitamins and minerals needed to provide for adequate nutrition in most healthy persons. The daily amount of chromium needed is defined in several different ways. If you think that you are not getting enough vitamins and/or minerals in your diet, you may choose to take a dietary supplement.Ĭhromium is found in various foods, including brewer's yeast, calf liver, American cheese, and wheat germ. For your specific dietary vitamin and/or mineral needs, ask your health care professional for a list of appropriate foods. Follow carefully any diet program your health care professional may recommend. Importance of Dietįor good health, it is important that you eat a balanced and varied diet. Other forms are available without a prescription. Injectable chromium is given by or under the supervision of a health care professional. There is not enough evidence to show that taking chromium supplements improves the way your body uses sugar (glucose tolerance). Lack of chromium may lead to nerve problems and may decrease the body's ability to use sugar properly. It is also needed for the breakdown of proteins and fats. Chromium helps your body use sugar properly. They are generally taken by mouth but some patients may have to receive them by injection. For patients who are unable to get enough chromium in their regular diet or who have a need for more chromium, chromium supplements may be necessary. The body needs chromium for normal growth and health.
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